Tara's other alters begin to disappear leaving only Bryce, who takes over Marshall's room and wreaks havoc on the Gregson family; Marshall moves in temporarily with his grandmother and mourns the loss of Lionel; Kate spends more time in St. Louis with Evan; Neil pressures Charmaine to move to Houston with him.

Everyone prepares to leave for uncharted waters as Tara and Max decide to go to Boston for help from the expert recommended by Dr. Hattaras; Neil and Charmaine prepare to move to Houston; Kate receives a life-changing proposal from Evan; Marshall considers the future of his education.