Jean and Anna arrive for their first day at St Angela's hospital. Jean, the new young casualty sister, soon discovers that life there is more explosive than she had imagined, whilst for Anna there is an unexpected arrival.

Katy's on night duty in charge of a noisy female surgical ward. When the day staff leave there are still two empty beds - one of them soon to be occupied by a fellow member of St Angela's nursing staff.

Sarah's problems are twofold; the Sister in charge of her ward and her depressed isolated patient. She decides to ask her father, the Senior Heart Consultant of the hospital, for help ...