Fifteen high school dropouts receive a last chance to get back into the education system. Dream School's 50 Cent and David Arquette introduce the kids to their new school and get to know them on a personal level.

Principal Dr. Keller brings inspirational celebrities Soledad O'Brien, Doriana Sanchez and Jeff Corwin to intervene in poor test grades. The kids are led through an emotional exercise, while a few remain unreachable.

If the students wish to succeed, all personal problems must be put aside at Dream School. Dr. Mae Jemison, Fabien Cousteau, Swizz Beatz, and Cliff Dorfman take the kids out of their comfort zone and help them get real.