VRC is at its limit when the amount of rescues and drop-offs rise; Lizzy and Toney travel to a remote part of the city to save a trio of orphaned dogs in a dire state; veteran tenant Lil Rocky faces a cancer scare.

Now a mother of two, Lizzy leans on Tia to help find a work-life balance; a California couple hopes to adopt a dog that will be comfortable in the pool; Mariah's mission to save an injured dog leads her to something completely unexpected.

At a Mississippi shelter, Tia gives a hybrid wolf-dog a second chance. At the vet, Lizzy is forced to make a tough call for a new VRC resident and later helps a pair of hearing impaired canines. Then, a California man visits to find a fur-friend.