On the streets of New Orleans, the VRC crew is on a mission to catch a runaway dog. A Californian family wants a new furry family member, a paralysed pup named Polly takes a trip to the vet, and Mariah pitches a fundraising idea to the parolees.

VRC is at its limit when the amount of rescues and drop-offs rise; Lizzy and Toney travel to a remote part of the city to save a trio of orphaned dogs in a dire state; veteran tenant Lil Rocky faces a cancer scare.

Now a mother of two, Lizzy leans on Tia to help find a work-life balance; a California couple hopes to adopt a dog that will be comfortable in the pool; Mariah's mission to save an injured dog leads her to something completely unexpected.