The police need Villalobos' help when a woman in the French Quarter is rushed to the hospital, leaving her dogs behind; a recent divorcee from Alabama visits the rescue to help fill the void in his home; Rhino faces a health crisis.

A family from Chicago comes to VRC hoping to find their first dog; in Assumption Parish, Tia takes in a dog that has been attacked and is near death; Earl mentors a young employee, trying to keep him out of trouble.

Former adopters want to expand their family and adopt Caleb, a puppy that Tania rescued at birth, but Tia is unsure he will fit in with their other dog. Also: when a local gets arrested, his dog is left behind and VRC is called in to help.