Election Day. The race is close, and while the candidates campaign, Kane and Stone must do their part to turn the gears of the political machine. Emma's world is turned upside-down while Meredith must go to great lengths to prove her allegiance to Kane.

Tom Kane cements his mayoral legacy with a lavish ceremony celebrating the groundbreaking of the new modernized O'Hare terminals. Now Kane looks to the future, setting his sights on reviving a subsidized housing project. While his political future seems bright, Kane continues to battle for control over his disease.

Kane uses personal tragedy to further his agenda, poaches his nemesis's aide, Mona, and hires ambitious newcomer Ian - but will they be enough to fill the void that Stone left behind?