In 1981, a gunman fires six shots at Ronald Reagan. What follows is a chaotic rush to save Reagan's life, confusion at the White House, and an urgent investigation to find out if this is a wider plot, or the work of a lone assassin.

In 1995, in an Oklahoma City federal building, a truck bomb killed 168 people. What caused a decorated war hero to carry out this attack?

Crimes of the Century examines the case of Amanda Knox an American exchange student living in Perugia who was arrested and accused of murdering her British flatmate Meredith Kercher. Knox is initially found guilty of the crime, but her argue that she is the victim of a out-of-control prosecutor and press.