After celebrating the release of his new book, Jonathan learns some distressing familial news. George reunites with his daughter Emily and Ray spends time with his biological son Spencer. Meanwhile, Jonathan's latest case leaves him in a precarious position.

On the run from the police, Jonathan and Ray turn to Howard for help with trying to find out who framed Jonathan for murder, while George runs interference for them in his own inimitable, marijuana induced way.

As a guest on 'The New Dick Cavett Show,' Jonathan runs into his nemesis. George is surprised to hear Bernard and Emily's news, and Ray sets off an AMBER Alert.