Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist. As the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

A massive tumor on Tim's neck continues to grow at an alarming rate, but doctors fear that removing it could leave him paralyzed.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor. Also, Amy has let the tumor on her back grow for more than 17 years. After finally making the decision to remove it, she learns that now it might be too late.