A well-known actor comes to Miami to star in a local play with Dorothy, Blanche and Rose, and soon begins seeing each one behind the others' backs. Meanwhile, Sophia gets a job at a pirate-themed fast food restaurant.

After having a throat spasm, Rose is convinced that she had an out of body experience. As a result, she decides to live life to the fullest -- which also gets in the way of Blanche and Dorothy's lives, but when they confront Rose about it, Rose decides to move out.

Sophia decides to enter herself into a charity walkathon, while Rose signs up herself, Dorothy and Blanche to babysit the children of the other participants. Once the walkathon is over, all of the kids are picked up -- except for one baby girl, who the girls fear has been abandoned.