Sixty-three-year-old Andrew is rushed in for urgent brain surgery to remove a tumour from the right side of his brain. Fifty-two-year-old Sarah undergoes a brain implant procedure in the hope of ending decades of excruciating cluster headaches. Also, 77-year-old Chris needs an operation to drill away the extra bone growth on his cervical spine.

Surgeons race to remove a life-threatening brain mass from 34-year-old Milton, operate on Annie's spinal tumour to prevent paralysis, and perform complex keyhole surgery on Rob's spine.

Sixty-four-year-old Bruce is rushed in with a broken back, and to make matters worse, a rare condition has fused his spine into a brittle, candle-like bone. Patient Keith is a medical mystery - his legs are failing, but scans reveal more questions than answers. Also, 62-year-old Linda faces an awake craniotomy to remove an aggressive brain tumour lying millimetres from the area that controls speech.