Mr. Terrific must locate the inventor of a hotly-pursued Power Paralysis device, unaware that the device is concealed in a book of matches in his coat pocket.

Stanley is assigned to locate and identify an elusive and mysterious crime boss known only as "Mr. Big".

When a distress call arrives about a malfunctioning Air Force One that Mr. Terrific could repair easily, Stanley discovers that his power pills inexplicably have stopped working.