Surgeon Kostas Papagiannopoulos must investigate a suspicious growth on a patient's lung, and cardiologist Andrew Hogarth treats a patient with a life-threatening infection.

Cardiac surgeon Betsy Evans operates on a patient needing a critical double bypass, and neurosurgeon Ryan Mathew performs awake brain surgery on a patient with a growing tumour.

Children's heart surgeon Osama Jaber must perform lifesaving surgery on a 15-day-old baby, and neurosurgeon Kenan Deniz operates on a patient suffering from debilitating headaches.