Neurosurgeon Ryan Mathew must rebuild a man's missing skull, and consultant Sheila Fraser removes a football-sized tumour from a patient's abdomen, suspected to be cancerous.

Plastic surgeon Chris West stops an anxious cancer patient from leaving, and neurosurgeon Kenan Deniz operates on a rare tumour behind a patient's ear that could paralyse her face.

Cardiac Surgeon Betsy Evans operates on her longest-waiting patient, and Professor Simon Kay aims to perform hand surgery on a teenage patient whose fingers are bent inwards.