At Leeds General Infirmary, Professor Simon Kay stands ready to perform a rare double hand transplant; in neurosurgery, Kenan Deniz has two patients needing urgent brain surgery.

Surgeon Naved Alizai operates on two children needing urgent liver surgery, and endocrine consultants Sheila Fraser and Emma Collins prepare to remove a tumour from a patient's neck.

Neurosurgeon Ryan Mathew must rebuild a man's missing skull, and consultant Sheila Fraser removes a football-sized tumour from a patient's abdomen, suspected to be cancerous.