After Kristin receives an email from another shelter located several hours away, she must quickly find a way to save two puppies before they are euthanized .An emaciated pitbull covered in mange has been rescued by a volunteer. The staff is horrified by his condition while they work to rehabilitate him. Meanwhile, Kristin must find a foster parent willing to handle such a hard case.

Pet Helpers saves 14 dogs from being euthanized at another shelter, but can Donya and Sarah manage the staff to handle this sudden surge of animals? Jason and Brian rescue a litter of feral puppies and are forced to care for them at Brian's house because the shelter is so overwhelmed.

Caroline organizes a puppy fashion show to get some new dogs adopted, but chaos erupts when several of them start acting up at the event. Will they all make it down the runway and find a forever home?