Best friends and fellow teachers John and Dave set out to teach the Cube a lesson, but learn that it's their relationship that's put to the test as they fight it out to try and win $250,000.

Can Dr. Libby and daughter Kelsey use their family bond to outwit The Cube as they continue on their quest to win big? Their ‘all or none' approach has left Dwyane Wade with his jaw dropped! Will they be the first to beat the Cube?

Cheer coaches Tommy & Jermaine tumble into The Cube. But can they turn their positivity into cold hard cash? We then meet brothers Brian and Branden from San Francisco, California. Could they be the first to crack the Cube?