Everybody has heard about Dracula, a blood-thirsty monster who invokes immortality with a bite on the neck. But many believe the real Dracula was a 15th century eastern European ruler with a penchant for impaling enemies, Vlad Tepes, whose curse upon his homeland has lasted for six centuries. With the help of emerging science in the field of genetics, Sam investigates the curse of Vlad the Impaler.

In 1915 in Louisiana, a local hoodoo practitioner and healer named, Aunt Julia, was enraged at the loggers cutting down her swamp so she invoked a curse on the people and the land. On the day of her death a deadly hurricane swept through the bayou destroying 3 towns and killing most of the people living in it. A century later, locals still blame all of the hardships in Louisiana on her curse.

Sam heads to the Mountain State to investigate the curse of the Mothman, a winged cryptid whose presence signals disaster. But, in a dangerous turn of events, Sam finds himself embroiled in a tangled web of disasters, population poisoning, physical threats and dirty politics in West Virginia.