An elephant is brought into the hospital with the suspected deadly herpes virus, and Paul helps the vets to try and save his life by attempting a blood transfusion. Elsewhere, Kat helps one of the oldest female elephants as she is treated for an infected foot and cameras also follow the largest herd in the hospital swimming in the river.

The vets check the heart health, dental health and gut health of their majestic patients, and a young bull elephant is rescued after breaking his leg in a violent thunderstorm. Later, laser technology is used to help save an elephant who has been brought into A&E with severe burns.

The work of a Thailand hospital devoted solely to treating elephants. In the final episode, Kat gets her hands dirty with elephant dung and conservationist Paul O'Donoghue helps the vets treat an infected abscess.