A baseball player unsettled by his ability to read the thoughts of others turns to NTAC for help and is instead used to spy on Jordan Collier. Meanwhile, Diana's younger sister visits; and Richard and Lily's life on the lam is complicated by their daughter's growing powers.

A 4400 with the ability to induce rapid weight loss attracts the attention of Tom and Diana; Richard, Lily and their child find refuge in the company of a fellow 4400; a pop star endorses Jordan's cause; and Kyle is caught up in the frenzy when a frat party gets out of control.

A schoolteacher terrifies parents with her supernatural ability to inspire artistic students; Richard, Lily and their child are cornered by the police; Jordan warns Shawn not to overuse his healing gift; and Kyle experiences another blackout.