In East London, at Newham Hospital A&E, a man suspected of being intoxicated causes a disruption and shouts at the nurses, causing a delay for other patients. A homeless woman is rushed to the hospital's resus department, after she was found collapsed in the street. At Belfast's Royal Victoria Hospital, nurse Rebekah deals with a man who has taken a cocaine overdose.

In East London, at Newham Hospital Emergency Department, doctors rush to save a 36-year-old man's sight, who has been violently attacked. Dr Rosie cares for a 63-year-old woman with a significant head injury in Newham. In Belfast, Dr Alice runs urgent tests to assess 83-year-old farmer Ian, who is suffering from suspected life threatening abdominal pain.

At Newham Hospital Emergency Department, a drunk man with knife wounds in his chest and hand refuses to cooperate, until heavy bleeding threatens his vital organs. In Belfast's Royal Victoria A&E, an 81-year-old woman has suffered a brutal injury to her leg from slipping in her muddy garden and smashing her shin into a concrete bar.