The night staff at Hull Royal Infirmary battle to save the sight of 51-year-old Patricia, who tripped and impaled her eye on a tent peg. With her vision impaired, a CT scan reveals a bleed on the brain that requires the intervention of neurosurgeon Dr Kenneth. Plus, a patient is flown in by air ambulance after falling down a ditch in her mobility scooter.

Lifting the lid on the night shift as experienced by A&E workers, with exclusive access to Hull Royal Infirmary. The night-time challenges facing NHS staff are captured in their raw form.

In North London security must manage an abusive man as he refuses to leave, despite being discharged and a patient suffering from a heroin overdose is rushed to Rotherham General Hospital's resus. Coming to his wit's end with a severe toothache, patient Kieran's abscess spreads to his airways and Doctor Mehran must decide whether he needs emergency surgery. Plus, security guard Justin suffers a head wound after being attacked when he tried to prevent a theft at his work.