Laird is infatuated with the sexual harassment seminar leader, Dorrit. To guarantee time alone with her, he claims he's being sexually harassed by the women in his office. Meanwhile Leila enlists Marmaduke's sign spinning skills to promote her real estate business, but he has to out-spin the competitors on the same street corner.

Dougie wins tickets to see his favorite rock band, the Spin Doctors, but Cindy refuses to go because she doesn't trust anyone to babysit their infant; Leila distributes flyers door-to-door in an effort to boost her real estate career, but a typo identifies her as a hooker; and Laird adopts a neighborhood dog who turns out to be a wild, dog-eating coyote.

Hot but vacuous Laird fears he may be losing his looks when he meets someone who's been dubbed "the handsomest man" in his office building, so to make himself more interesting to women, Laird starts to take clarinet lessons. In the meantime, while guarding one of Leila's properties, Marmaduke falls for the girl who tagged Leila's flip.