Bob the Drag Queen, Eureka O'Hara, and Shangela Laquifa Wadley arrive in Gettysburg, Pennsylvania to put on a one-night-only drag show featuring locals in need of a little support and empowerment, including: Hunter, a young, gay make-up artist yearning for a deeper connection with his father; Darryl, a local college admissions officer hoping to tell a story of race in America while being an effective ally to the LGBTQ community; and Erica, a conservative Christian mother eager to reconnect with her estranged daughter Hailey, who recently came out as bisexual.

Bob, Eureka, and Shangela head west to Twin Falls, Idaho, a conservative, predominately Mormon community in Magic Valley. There, they meet Michael, Owen, and Amelia, a group of local drag artists who need help forming a community. In order to do just that, the queens work with: Clifton, a young, straight musician trying to make amends for his past by testing his definition of masculinity; and Brandon, a trans man, and his wife, Mikayla - high school sweethearts from religious families - who are looking for the wedding experience they didn't have the first time around.

In Branson, Missouri, a wholesome showbiz town smack in the middle of the Bible Belt, Bob, Eureka, and Shangela help three locals struggling to be their true selves in a community that prides itself on its traditional, religious values. Among them are Tanner, a young actor questioning whether it's possible for him to be both Christian and gay; Charles, a classically-trained dancer who wants to show that he's not just out, but proud; and Chris, a father grappling with mental health issues who's determined to embrace his emotions for the sake of his daughter.