Rufus finds himself forced to take part in Dr. Mu's malevolent game show, Cash or Kick Yourself, which he is broadcasting to every civilised planet in the multiverse. To save the world, Rufus must successfully complete every round of the show, evade the show's dubious mascot, Mr. Blinko, and win the mystery prize.

The world's superheroes have gone missing! As Earth is gripped by chaos, crime waves and cats stuck up trees, Rufus reluctantly pulls on a pair of extremely suspect underpants - courtesy of his Future Self - and heads to the Planet Invincible to save the day.