Documentary featuring Britain's most prolific hoarders, from the man whose clutter was so vast he could no longer get through his front door to the woman whose home hid the remains of dead animals. Others include Richard, who has been keeping mountains of newspapers for many years in the name of research, Arthur, who refuses to part with his collection of important personal memories and Mandi, whose impressive collection of vintage clothing has taken over most of her home.

Clinical psychologist Dr Zasio immediately calls the Child Protection Services after inspecting a mother's house.

Tami is battling cancer and her last hope for survival is a bone marrow transplant. But the condition of her home is getting in the way of her treatment.