Ben's dream of working with children turns into a nightmare when he is faced with little Alfie's tears and tantrums. Sameer is called to his first real emergency, where he is confronted with the harsh reality that he cannot save every patient.

The junior doctors are learning to deal with challenging patients and situations. On A&E, Amieth deals with a barmaid who has come in with a receipt spike through her hand, while on the surgery ward Andy has to convince a patient to stop eating before an operation.

The hospital has decreed that all junior doctors wear white coats so that patients can identify them, but not everyone is happy with the new look. Lucy struggles to keep up with the demanding workload on the nightshift.