Black Panther, the king of a secretive high-tech African tribe, challenges the Fantastic Four. Once defeated, he asks for their help to stop Ulysses Klaw, a mad scientist who killed his father and wants the tribe's powerful alien ore.

Galactus' new slave and herald, double-crossing Terrax, asks Fantastic Four for help. However, Johnny's Inhuman girlfriend Frankie supports Galactus. Thor arrives to help the Fantastic Four and even mythical Ghost Rider intervenes.

Dr. Doom manipulates the unstoppable Hulk into fighting the Fantastic Four. Only the Thing's girlfriend Alicia can help.