Ego, the Living Planet, a unique monster planet that devours planets just like Galactus, enters the solar system to eat Earth.

Black Panther, the king of a secretive high-tech African tribe, challenges the Fantastic Four. Once defeated, he asks for their help to stop Ulysses Klaw, a mad scientist who killed his father and wants the tribe's powerful alien ore.

Galactus' new slave and herald, double-crossing Terrax, asks Fantastic Four for help. However, Johnny's Inhuman girlfriend Frankie supports Galactus. Thor arrives to help the Fantastic Four and even mythical Ghost Rider intervenes.