The Fantastic Four stops the Skrulls once again, but Sue ends up in a coma and her dad is framed. The Skurlls also send Super-Skrull again, this time masked as Sue. Meanwhile, Skrull warlord Morrat tries to take over the Skrull empire.

Impish alien trickster dubbed the Impossible Man and Inhuman Lockjaw help the Fantastic Four fight the Super-Skrull.

The Fantastic Four help Black Bolt save his people - the Inhumans - who live imprisoned under an unbreakable dome guarded by a simple, but relentless robotic sentry, who misunderstood his orders to protect the Inhumans forever.