It's a week of ups and downs at Dr. K's clinic when Paco, a seven-year-old sun conure, has a giant egg that won't come out, Pepe, a seven-year-old kinkajou, has burns on his tail and back paws, and Shar, a one-year-old prairie dog, has a big lump on his belly. And the staff must give bittersweet farewell to a beloved colleague as Dr. Thielen's time working at the clinic comes to an end.

This week, Coco the Guinea Pig has a recurring abscess, and x-rays reveal a huge problem; an emotional support goat named Dexter is showing signs of pneumonia, and Bluebi, an Indian ringneck parakeet, is in such a fragile condition that Dr. K fears handling him could even be fatal.

Time is of the essence as Dr. Oakley races to diagnose a cat with an extreme bladder issue. A farm well-equipped for handling cattle needs help testing out a new system for some rowdy bison, and Dr. Oakley hosts a drive-thru vaccination clinic. Dr. Oakley checks on two ferrets as well as two German Shepherds with ailments common to their breeds.