Dr. K and her team are preparing for surgery on Bob the sulcata tortoise, who was brought in with a mass on his neck, likely a puncture wound caused by humping a stack of wood. At the same time, an emergency case is rushed into the treatment room. Shelby, a 9-year-old chinchilla, is bleeding from the mouth and the cause is unknown. Dr. K rushes to solve the case before the fragile animal loses too much blood. Meanwhile, Dr. Thielen takes on a mystery case involving a therapy chicken with a lame leg. The diagnosis leaves the owner faced with a heart-wrenching decision, while Mimi the pot-bellied pig is put to the weight loss test after being put on a diet.

Tension is high as many critical patients visit the clinic. First, two sugar gliders are rushed in to receive treatment after getting tangled in a blanket and fighting their way out. Dr. Thielen checks out a newly adopted cockatiel that flew into a flytrap and has sticky material all over its feathers. Finally, a long-time bunny patient has an obstruction in her stomach that needs to be removed immediately.

Dr. K's day kicks off with an emergency when a bleeding cockatiel comes into the clinic. Dr. Thielen sees three animals in one appointment including a skunk that needs to be spayed and two panther chameleons in for a wellness check. Then Dr. K finds a litany of ailments in a 9-year-old ferret and must manage its care and quality of life. Meanwhile, a quaker parakeet's owners are concerned about a tumor, only to find out that the bird is so obese that it must lose a third of its body weight and see a heart specialist. Dr. Thielen tries to relieve a gerbil of an abscess, while Dr. K cleans a mouth wound on a boa constrictor so unpleasant it affects the entire clinic.