Dr. K starts this challenging day with Chloe, a 6-year-old guinea pig who is having a seizure. A catheter is inserted to get fluids and medications into the guinea pig. Dr. K then moves on to Jed, a ferret who was once bright and active, but now has a fever and is completely lethargic. Dr. K thinks he may have perforated his intestine, but it is even worse than she feared. Suddenly a cockatiel arrives, bleeding from the mouth. Dr. Diaz rushes her to the surgery room, with Dr. K close behind. At the end of the day, Dr. Thielen must help a woman say goodbye to a cherished pet.

Some days are more about educating pet parents than treating patients. Dr. K confronts an owner who is taking their marmoset on public outings. This is extremely dangerous for the marmoset and humans, as diseases can pass between them. Dr. Diaz sees a kinkajou with a breathing problem. The owners are making a husbandry mistake by keeping their house too cold for her. Kinkajous are from the much warmer climates of southern Mexico and Central and South America. Finally, Dr. K gets to see the fruits of her labor as she joins the South Florida Wildlife Center for a rehabbed pelican release.

It's business as usual at Dr. K's exotic animal E.R., until a stressed out Eurasian lynx is brought in for over-grooming and not eating. Dr. K suspects a large hairball to be at the root of the problem, and contemplates emergency surgery on the large cat. Dr. Thielen sees two emergency cases of her own, including a ball python that was brutally attacked by a feeder rat, and a rescued cockatiel that is in distress, trying to lay an egg. A lame baby chicken gets a new lease on life, while a recently neutered pot-bellied pig continues to heal and hopefully get rid of his "boy juices" smell.