The Temperance movement takes hold in Great Bend after a slew of alcohol-related deaths. However, when the saloon goes booze free, Honey resorts to selling "medicine" to keep the bar in business.

When the U.S. Marshalls unfairly suspect an ex-slave of murder, Sheriff Hoyle must clear his name by tracking the real killer to the all-black town of Nicodemus, led by Sheriff Nat Love.

When Honey's long-lost fiancé surfaces in Great Bend, he challenges Hoyle to a duel when he learns of their ongoing "relations." Meanwhile, things start to get more serious between Eli and Pearl.