Much to Hoyle's chagrin, Eli purchases a mail order bride, but when the coach arrives with Eli's precious cargo, its contents send the duo into an unexpected tailspin.

In the wake of a gruesome decapitation, Hoyle uses the latest in crime-fighting techniques to apprehend the killer, but when the evidence points in an unexpected direction, Hoyle must persuade the town to listen to science.

The Temperance movement takes hold in Great Bend after a slew of alcohol-related deaths. However, when the saloon goes booze free, Honey resorts to selling "medicine" to keep the bar in business.