When Frank James attempts to rob the Great Bend Bank, Hoyle and Eli save the day and jail the famous outlaw.

Much to Hoyle's chagrin, Eli purchases a mail order bride, but when the coach arrives with Eli's precious cargo, its contents send the duo into an unexpected tailspin.

In the wake of a gruesome decapitation, Hoyle uses the latest in crime-fighting techniques to apprehend the killer, but when the evidence points in an unexpected direction, Hoyle must persuade the town to listen to science.