Dr. Williams uses ultrasound to test Shadow the golden retriever for heartworms and Dr. Boyd attempts to treat Tiger the cat's severely burned paws after a tragic house fire.

Dr. Williams finds that elderly cat Chloe may have hypertrophic cardiomyopathy and Dr. James suspects that internal bleeding from a knitting needle injury may be causing Alien the cat's motor function issue.

Dr. Boyd treats a cancerous tumor on Dudley the miniature poodle's jaw, Dr. Martin tests Kaileigh the dog's spleen while looking for the cause of nausea and restlessness and doctors seek the cause of Loki the kitten's heart murmur.