When Chihuahua Reilly breaks a leg, Dr. Boyd performs surgery, a cat named Jerry survives a house fire, but his gums suffer due to smoke inhalation and Dr. Williams consults with Dr. Cochrane to treat Cyril the cat's high blood pressure.

Dr. Boyd and Arnold the Mastiff's owner decide it's best to amputate a portion of his tail, a Pomeranian named Rosie needs a long overdue teeth cleaning, but may not be a good candidate for surgery and an older ferret named Jet is treated for influenza.

Dr. Boyd's own pup needs surgery to repair his knee, Dr. Bryer tries to help Trigger the cat, who is in need of serious relief and Dr. Bryer and Dr. James team up to help an aging cat who's unable to walk.