While making their way in the world, the terror the friends been avoiding suddenly strikes at their heart in the most unexpected manner. Reeling from the news, everyone has to rally round. And when a hospital takes shocking action, the flatmates must fight like never before.

March 1988. Ritchie embarks on a lonely journey home. Meanwhile, Jill is in danger, and Roscoe's set to collide with Margaret Thatcher, as protests about the AIDS crisis begin.

1991. The flatmates rally round as they enter the darkest days of their lives. When Valerie goes on the warpath, it's up to Jill to help Ritchie before it's too late.