What is life in prison really like for the fastest growing segment of incarcerated Americans? Chris Cuomo is granted unprecedented access to New York State's only maximum security prison for women, witnessing some of the most important moments of some of the inmates' lives.

Cuomo goes inside a maximum-security prison for an exclusive interview with one of America's most notorious serial killers, Joel Rifkin. Cuomo is Rifkin's mind-hunter, asking him tough questions about his sordid sex life, why he brutally murdered 17 women and how he was eventually caught. Beyond the horrors of the killings themselves, Cuomo tries to understand what motivated Rifkin, who is serving more than 200 years for his grizzly yet methodical crimes.

Julie was abducted from her church parking lot by a stranger. Gabrielle was attacked as she walked home from work alone at night after the Uber app on her phone malfunctioned. Despite the growing attention on sexual assault, an alarming number of rapes go unpunished; more than 98% of the time the perpetrators never spend a single day in prison. Cuomo hears the firsthand accounts of rape survivors and examines what hurdles they face to get justice.