Freddie is prescribed painkillers to treat a nagging injury he suffered playing basketball ... and soon becomes hooked. His friends become concerned about Freddie's increasingly scary behavior, but "Boom-Boom" tries to brush them off - after all, it's just "vitamins." What becomes even more scary is that Horshack blindly believes his friend's explanation, even though it becomes clear that Freddie needs help before something goes horribly wrong.

Vinnie blames himself for his shop teacher's fatal heart attack, which came on while Mr. Kripps was yelling at him.

Arnold is depressed because no girl will go out with him. After Mrs. Kotter consoles him and helps him find his confidence, he falls in love with her.