New roles for the junior doctors bring with them their own challenges. Rhian faces huge pressure in work and her private life suffers as a result, whilst Simon searches for the meaning of true love. Though love may come and go, Rhian realises that friendship is forever.

It should be a quiet Sunday night shift, but with a suicidal radio DJ, a quest to save the work of a doctor's lifetime and Ameer's stalker to deal with, the gang have their work cut out.

Cath, Rhian and Ameer try to discover why Simon is convinced of his own early demise. Simon helps Sister Alice with a special secret project.