Jess is a widower looking for love who is stuck with a giant bump on his neck. Cherish developed a leopard-print face during pregnancy. Former NFL defensive tackle Marcell Dareus hopes Dr. Lee can tackle his forehead lipoma.

Brent has a tricep bump potentially intertwined in his muscle; Jeb loves the beach but refuses to go because of the massive number of blackheads, pimples, and cysts all over his body; Wanda's mysterious mark that caves in her side.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.