Bob suffers from mysterious open-wound sores all over his body; Virginia's stress-ball-sized lump is such a pain in her neck that she can't wait to have it removed; Ted suffers from flaking, itchy, stucco-like skin and has had no luck finding a cure.

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps all over her arms, chest and belly. Gabe cannot imagine going to college with the unsightly mole on the back of his head.

Steven's bump is so large, his daughter thinks he is growing a monster on his back. Catherine's arm lump has grown so big that it's nearly up to her armpit. Ethan suffers from an irritating rash in an uncomfortable and awkward place on his body.