Robert has thousands of unique bumps on his arms that Dr. Lee has never seen. Alexis has a painful cheek cyst that oozes and has a pungent odour. Stuart's cluster of back bumps disgusts his wife, but thrills Dr. Lee.

Casey's birthmark covers most of her face, head and neck. James has mysterious growths on his inner thigh and lower abdomen that are completely puzzling. Jerry had to hang up his rock star vocal cords when a lump grew out the side of his throat.

Elizabeth's head is covered with giant cauliflower-shaped bumps. Jamaal has been growing a strange knob on the left side of his butt since he was just a boy. Donna's cracking, bleeding skin condition has aged her face and kept her from being social.