Eric hopes Dr. Lee is able to remove the giant growth from his behind. Breanna suffers from itchy dry skin she can't help but scratch. Michael makes jokes, but he knows the bump on his head is anything but funny.

Johnnie's crippling psoriasis keeps him from spending time with his daughter. Aimee has a mohawk of cysts on her head. Edith's face markings and itchy skin condition turn out to be more than she expected.

Dr. Lee faces off with iguana-wrangler Madison's head growths; Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats; the dark purple birthmark on Eddie's nose has made him a recluse.