Keke is covered in bumps that make her embarrassed to be intimate with her husband. Jim is a widower with two lumps who wants them removed for himself and his late wife. Corey has been labelled a devil worshipper because of his forehead growth.

Stacey has a growth on her shoulder that prevents her from being the playful teacher she once was. Matthew has a mysterious rash on his shin and worries it may be dangerous. Mark has a growth in his pubic area that has put a damper on his sex life.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast.