Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.