Inoke has a huge, possibly life-threatening bulge on his shoulder. Delano returns with his back lump after Dr. Lee removed a liter of fluid from it. Reed has hundreds of bumps on his chest that burst and leave nasty scars.

Tony has large growths on his nose that impair his breathing. Kevin has a bump in his jawline that is a "lady deterrent."  Marie has an unsightly lump on her forehead that makes her a hermit.  Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body, Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.